BRCA1

Organism Phenotypes

In humans, mutations in BRCA1 clearly lead to breast cancer and ovarian cancer. What kinds of phenotypes are found in other organisms. Most of what I have focused on is in model organisms less closely related to humans.

RNAi
Use of siRNA to somewhat transiently knock down gene expression in smaller organisms

Small molecules
Tests for small molecules that inhibit all or specific functions of a protein, or may be activating